Brooks Glycerin 21 vs Glycerin 22
Updated August 3, 2026. Specs are men's US 9.
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THE SHORT ANSWER
Whichever your size still exists in. The Glycerin 21 is discontinued at retail, so remaining pairs sell against a thinning size run, while the Glycerin 22 has a full one. The Glycerin 21 also lists $5 lower.
- Brooks Glycerin 21Men's at AmazonWomen's
- Brooks Glycerin 22Men's at AmazonWomen's
Availability last checked Aug 3, 2026. Prices and stock change without notice.
Every spec, side by side
| Spec | Glycerin 21 | Glycerin 22 |
|---|---|---|
| FIT AND WEIGHT | ||
| Weight | 9.8 oz | 10.2 oz |
| Widths | D, 2E | D, 2E, 4E |
| Upper | Engineered warp knit | Engineered mesh |
| Roomier toebox, but several longtime wearers found the midfoot and arch tighter than their 20s and 21s in the same size. | ||
| CUSHIONING GEOMETRY | ||
| Heel stack | 38 mm | 38 mm |
| Forefoot stack | 28 mm | 28 mm |
| Drop | 10 mm | 10 mm |
| MATERIALS | ||
| Midsole | Nitrogen-infused DNA Loft v3 | DNA Tuned supercritical foam |
| The reboot foam, inherited from the Glycerin Max: large soft cells in the heel, small firm cells in the forefoot, one glue-free slab. It is measurably stiffer than v3 and firms up further in the cold (a lab measured a 33 percent firmness increase). | ||
| VALUE | ||
| List price at launch | $160 | $165 |
| OTHER CHANGES | ||
| Widths | Normal and Wide | Normal, Wide and X-Wide |
| First 4E option in the line. | ||
Weighing whether to switch at all, rather than which of these two to buy? What replaced the Brooks Glycerin 21 covers the verdict on the update, what loyalists made of it, and the closest alternatives from other brands.
Buy the Glycerin 21
Stocked at AmazonAvailability last checked Aug 3, 2026.
Buy the Glycerin 22
Stocked at AmazonAvailability last checked Aug 3, 2026.
Questions runners ask
- Which is lighter, the Brooks Glycerin 21 or the Glycerin 22?
- The Brooks Glycerin 21, by 0.4 oz in a men's US 9 (9.8 oz vs 10.2 oz).
- Did the price change between the Brooks Glycerin 21 and the Glycerin 22?
- Yes. List price went up $5, from $160 to $165. Street prices differ: the older shoe usually sells under list once its successor ships.
- Do the Brooks Glycerin 21 and Glycerin 22 come in the same widths?
- No. The Brooks Glycerin 21 came in D, 2E; the Glycerin 22 runs in D, 2E, 4E. The Glycerin 22 added 4E.
- How do the stack heights compare?
- 38 mm heel and 28 mm forefoot on the Brooks Glycerin 21, against 38 mm and 28 mm on the Glycerin 22. Same platform under both.
- Is the Glycerin 22 still the newest Glycerin?
- No. The Glycerin 23 replaced it in 2026, so the Glycerin 22 now sells as an older model and usually below its $165 list price.