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Nike Pegasus vs Saucony Endorphin Speed

Comparing the current Pegasus 42 and Endorphin Speed 6. Specs are men's US 9.

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THE SHORT ANSWER

Drop is the real difference: 8 mm on the Endorphin Speed 6 against 10 mm on the Pegasus 42. Coming off the Pegasus 42, the Endorphin Speed 6 loads your calves and Achilles harder for the first couple of weeks. They are built for different jobs: the Pegasus 42 is a daily trainer, the Endorphin Speed 6 a tempo. The Pegasus 42 lists $30 lower.

Availability last checked Jul 31, 2026. Prices and stock change without notice.

Nike Pegasus 42, men's shoe, side profile
Pegasus 42 · 2026
Saucony Endorphin Speed 6, men's shoe, side profile
Endorphin Speed 6 · 2026

Every spec, side by side

SpecPegasus 42Endorphin Speed 6
FIT AND WEIGHT
Weight10.1 oz7.8 oz
WidthsD, 2ED, 2E
UpperRedesigned engineered mesh on a more anatomical last with a roomier toeboxLightweight engineered mesh
CUSHIONING GEOMETRY
Heel stack37 mm39 mm
Forefoot stack27 mm31 mm
Drop10 mm8 mm
MATERIALS
MidsoleReactX foam with a full-length curved Air Zoom unitPWRRUN PBX foam
PlateNoneRedesigned nylon plate
VALUE
List price at launch$145$175

Which line changes its ride more often?

The Pegasus has done it once in 6 versions, most recently with the Pegasus 41 in 2024, and the Endorphin Speed has done it 3 times in 6 versions, most recently with the Endorphin Speed 6 in 2026. If you want a shoe you can rebuy without reading a review first, the Pegasus has the steadier record.

Buy the Pegasus 42

Stocked at Amazon

Availability last checked Jul 28, 2026.

Buy the Endorphin Speed 6

Stock unverified

Availability last checked Jul 31, 2026.

Chasing a specific older version rather than choosing between the current two? The Nike Pegasus lineage and the Saucony Endorphin Speed lineage track every version and what changed in each update.

Questions runners ask

Is the Nike Pegasus or the Saucony Endorphin Speed lighter?
The Endorphin Speed 6, by 2.3 oz in a men's US 9 (7.8 oz against 10.1 oz).
Can I switch from the Nike Pegasus to the Saucony Endorphin Speed?
Yes, but ease into it. The drop moves 2 mm (10 mm on the Pegasus 42, 8 mm on the Endorphin Speed 6), which changes where your foot loads at landing. Give it two weeks of easy running before a hard session.
Which is more cushioned, the Nike Pegasus or the Saucony Endorphin Speed?
The Endorphin Speed 6, on stack height: 39 mm under the heel against 37 mm. Stack is not the whole story, though; the foams differ too.
Which costs more, the Nike Pegasus or the Saucony Endorphin Speed?
The Endorphin Speed 6, by $30 at list ($145 against $175). That gap narrows once either one gets a successor.

Updated July 31, 2026.